Publications

Manuscripts

Multicancer Screening: One Size Does Not Fit All

Journal of Clinical Oncology: Precision Oncology

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

BMC Cancer

Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection

Nature Communications

Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data

Journal of Proteome Research

Posters

Study Population Analysis of PREEMPT CRC Using a Multiomics Blood Test for the Early Detection of Colorectal Cancer

2023 Western CRC Consortium Conference

Identification of predictive biomarkers for response of R/R DLBCL patients treated with loncastuximab tesirine using low-pass whole-genome cell-free DNA sequencing (cfDNA-WGS)

2022 ASH

Interception versus prevention in cancer screening in a Medicare population: Results from the CRC-MAPS model

2022 ASCO

Adenoma detection improves clinical outcomes across adherence scenarios for a CRC screening blood test meeting CMS performance targets: Results from the CRC-MAPS model

2022 DDW

Fact or Myth: Black Patients Do Not Want to Participate in Clinical Trials

2022 DDW

Liquid biopsy-based multiomics profiling reveals molecular features of disease severity in EGFR/ALK wildtype NSCLC patients

2022 AACR

Interception versus prevention in cancer screening: Results from the CRC-MAPS model

2022 AACR

Multi-level factors reported in colorectal cancer screening adherence studies reflect evolving challenges and opportunities in different care settings: A systematic review

2022 ASPO

Prevention of Colorectal Cancer Through Multiomics Blood Testing: The PREEMPT CRC Study

2022 ASCO-GI

Enrollment Rate Of African Americans In A Colon Cancer Screening Trial at a Historically Black College and University is Similar to Other Patient Populations

2021 ACG

Burden-to-benefit ratios differ by adenoma size: Results from the CRC-MAPS™ model

2021 ACG

Frequency And Co-Occurrence Of Younger Age And CRC Screening Barriers: A Systematic Review And Bibliometric Analysis

2021 ACG

Design and Implementation of a Clinical Study to Validate a Multiomics Blood Test for Colorectal Cancer Screening

2021 AAFP FMX

Plasma-based detection of pancreatic cancer: A multiomics approach

2021 AACR Special Conference: Pancreatic Cancer

Test interval and adherence have comparable impacts on colorectal cancer (CRC) incidence and mortality reduction: Results from a novel microsimulation model

2021 DDW

Adenoma Sensitivity Has A Greater Impact On Colorectal Cancer (Crc) Incidence And Mortality Reduction Than Crc Sensitivity Or Specificity: Results From A Novel Microsimulation Model

2021 DDW

Whole genome cfDNA profiles reveal common signatures of immune checkpoint inhibition in kidney, melanoma, and lung cancers

2021 AACR

Evaluation of a sensitive blood test for the detection of colorectal advanced adenomas in a prospective cohort using a multiomics approach

2021 ASCO-GI

Multiomic plasma profiling identifies potential signatures of disease progression in early-stage NSCLC

2020 AACR

Plasma-derived cfDNA reveals potential biomarkers for response prediction and monitoring in NSCLC patients on immunotherapy

2020 ASCO

Blood-based detection of early-stage colorectal cancer using multiomics and machine learning

2020 ASCO GI

Exploratory longitudinal analysis of cfDNA reveals potential biomarkers of mCRC progression and treatment response

2020 ASCO GI

Predicting gene expression from plasma cell-free DNA using both the fragment length and fragment position

2019 AACR

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

2019 AACR

Latent Representations from Factor Analysis and CNNs of Genomic and Proteomic Data Reveal Immune Pathways in Colorectal Cancer

2019 NeurIPS

METCC: METric learning for Confounder Control Making distance matter in high dimensional biological analysis

2018 NeurIPS

Bridging the Generalization Gap: Training Robust Models on Confounded Biological Data

2018 NeurIPS

Publications

Manuscripts

Multicancer Screening: One Size Does Not Fit All

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

Inference of transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection

Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data

Posters

Study Population Analysis of PREEMPT CRC Using a Multiomics Blood Test for the Early Detection of Colorectal Cancer

Identification of predictive biomarkers for response of R/R DLBCL patients treated with loncastuximab tesirine using low-pass whole-genome cell-free DNA sequencing (cfDNA-WGS)

Interception versus prevention in cancer screening in a Medicare population: Results from the CRC-MAPS model

Adenoma detection improves clinical outcomes across adherence scenarios for a CRC screening blood test meeting CMS performance targets: Results from the CRC-MAPS model

Fact or Myth: Black Patients Do Not Want to Participate in Clinical Trials

Liquid biopsy-based multiomics profiling reveals molecular features of disease severity in EGFR/ALK wildtype NSCLC patients

Interception versus prevention in cancer screening: Results from the CRC-MAPS model

Multi-level factors reported in colorectal cancer screening adherence studies reflect evolving challenges and opportunities in different care settings: A systematic review

Prevention of Colorectal Cancer Through Multiomics Blood Testing: The PREEMPT CRC Study

Enrollment Rate Of African Americans In A Colon Cancer Screening Trial at a Historically Black College and University is Similar to Other Patient Populations

Burden-to-benefit ratios differ by adenoma size: Results from the CRC-MAPS™ model

Frequency And Co-Occurrence Of Younger Age And CRC Screening Barriers: A Systematic Review And Bibliometric Analysis

Design and Implementation of a Clinical Study to Validate a Multiomics Blood Test for Colorectal Cancer Screening

Plasma-based detection of pancreatic cancer: A multiomics approach

Test interval and adherence have comparable impacts on colorectal cancer (CRC) incidence and mortality reduction: Results from a novel microsimulation model

Adenoma Sensitivity Has A Greater Impact On Colorectal Cancer (Crc) Incidence And Mortality Reduction Than Crc Sensitivity Or Specificity: Results From A Novel Microsimulation Model

Whole genome cfDNA profiles reveal common signatures of immune checkpoint inhibition in kidney, melanoma, and lung cancers

Evaluation of a sensitive blood test for the detection of colorectal advanced adenomas in a prospective cohort using a multiomics approach

Multiomic plasma profiling identifies potential signatures of disease progression in early-stage NSCLC

Plasma-derived cfDNA reveals potential biomarkers for response prediction and monitoring in NSCLC patients on immunotherapy

Blood-based detection of early-stage colorectal cancer using multiomics and machine learning

Exploratory longitudinal analysis of cfDNA reveals potential biomarkers of mCRC progression and treatment response

Predicting gene expression from plasma cell-free DNA using both the fragment length and fragment position

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

Latent Representations from Factor Analysis and CNNs of Genomic and Proteomic Data Reveal Immune Pathways in Colorectal Cancer

METCC: METric learning for Confounder Control Making distance matter in high dimensional biological analysis

Bridging the Generalization Gap: Training Robust Models on Confounded Biological Data

Multi-Analyte Profiling Reveals Relationships Among Circulating Biomarkers in Colorectal Cancer

Limitations on Mutation Detection for Early Detection of Cancer

White Papers

Research Into the Clinical Potential of Cell-Free DNA